科研成果 - 艾克发（北京）生物技术

Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma

Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators

发布期刊：Cancer Cell

Efficacy and safety of PD-1 blockade plus long-course chemoradiotherapy in locally advanced rectal cancer (NECTAR): a multi-center phase 2 study

发布期刊：Signal Transduction and Targeted Therapy

影响因子IF：39.3

疾病类型：晚期直肠癌

发布时间：2024-05-11

团队：首都医科大学附属北京友谊医院普外科张忠涛教授和姚宏伟教授等团队

阅读次数：115

Patient-Derived Tumor Organoids Combined with Function-Associated ScRNA-Seq for Dissecting the Local Immune Response of Lung Cancer

发布期刊：Advanced Science

影响因子IF：14.3

疾病类型：肺癌

发布时间：2024-06-29

团队：清华大学医学院生物医学工程系刘鹏研究员
北京大学人民医院王俊院士
北京航空航天大学陈晓芳副教授

阅读次数：178

Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment

发布期刊：Alzheimers & Dementia

Spatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells

发布期刊：Cancer Research (AACR)

影响因子IF：11.2

疾病类型：头颈部鳞状细胞癌 (HNSCC)

发布时间：2024-01-16

团队：张建军团队（马海龙、张志远）上海交通大学医学院附属第九人民医院口腔颌面头颈肿瘤科

阅读次数：129

Landscape of gut mucosal immune cells showed gap of follicular or memory B cells into plasma cells in immunological non‐responders

发布期刊：Clinical and Translational Medicine

影响因子IF：10.6

疾病类型：胃肠道粘膜；HIV病毒

发布时间：2024-05-14

团队：301第一医学中心消化内科主任医师令狐恩强团队

阅读次数：132

A breast cancer classification and immune landscape analysis based on cancer stem-cell-related risk panel

发布期刊：npj Precision Oncology

影响因子IF：9.3

疾病类型：乳腺癌

发布时间：2023-12-08

团队：南华大学附属第一医院药学部张陶蓝博士

阅读次数：176